Tottenham Hotspur head into a tie with FC Sheriff looking for a fourth Europa League success and a place in the knockout stage.
Spurs boast an unblemished record in continental competition this season, with maximum points taken from their three fixtures so far.
A point is all they require on Thursday to make it safely through to the last 32 with two games to spare.
Andre Villas-Boas' troops will also be looking to preserve their perfect defensive record, with a watertight back four yet to be breached in Europe.
It is likely that the pack will be shuffled again in midweek, with Spurs now boasting the strength in depth required to compete on multiple fronts.
Whatever line-up they go with, they will feel that they have enough to see off Sheriff at White Hart Lane - having already claimed a 2-0 victory over the Moldovan champions on the road.
Jermain Defoe could be among those selected by Villas-Boas, with the England international in need of one more goal to become Spurs' all-time leading scorer in Europe.
Hugo Lloris is in contention to start Tottenham after taking part in training on Wednesday morning.
Goalkeeper Lloris has been passed fit despite being knocked unconscious in a collision with Everton's Romelu Lukaku on Sunday.
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Villas-Boas says either Lloris or Brad Friedel will start the Group K clash, but he will not make that decision public until an hour before the game.
Defender Danny Rose (toe), midfielder Sandro (hamstring) and left-back Zeki Fryers (groin) are out while Villas-Boas says striker Emmanuel Adebayor will not feature.
Sheriff will be looking to call upon the momentum they have built at domestic level, with a seven-point lead opened up at the top of the Moldovan National Division.
Coach Veaceslav Rusnac believes his fully-fit squad are capable of taking something from a trip to England, with there only two points separating his side from Anzhi Makhachkala in the battle for second spot.
He said: "By now everyone is healthy and ready to take the field.
"We are not going to London just to have a regular game on the field. We are coming to get points because we want to play in Europa League in spring."
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